Pengaruh Pemberian Calcitriol terhadap Kadar Limfosit pada Tikus Putih (Rattus norvegicus) Galur Wistar Jantan yang Dipapar Asap Rokok

The health impact for active and passive smokers is damage to the organs respiratory tract. body initially experience inflammation which increases number of white blood cells, one an increase in lymphocytes. One efforts reduce caused free radical by cigarette smoke consuming Calcitriol. Objective: To determine effect presenting Calcitriol on lymphocyte levels male Wistar rats (Rattus norvegicus) exposed smoke. Methods: This type research a pure experimental (true-experiment) using pre post-test design with control group check norvegicus). 24 were divided into 6 groups simultaneously. Random, namely 1 (exposed not given Calcitriol), 2 placebo olive oil), treatment dose 0.25 µgr / head), at 0.5 head) 3 head). Results: Paired t-test showed evidence that stated (p <0.05) K2 = 0.014), K3 0.049), P1 0.012) P3 (0.001) . Meanwhile, K1 0.115) P2 0.066) had no statistical difference. Conclusion: administration can